Liver inflammation linked to cancer interferes with immunotherapy effectiveness via SAA protein secretion.
Liver inflammation linked to cancer elsewhere in the body may hinder immunotherapy effectiveness. Researchers from Penn's Abramson Cancer Center & Perelman School of Medicine found that cancer-induced liver inflammation causes liver cells to secrete SAA proteins, which interfere with T cells' ability to attack tumors. Understanding this relationship could lead to improved cancer treatment strategies.
April 19, 2024
3 Articles