A new cancer treatment, ALG.APV-527, shows promise with positive phase 1 trial results, benefiting 56% of patients.

Aptevo Therapeutics and Alligator Bioscience have reported positive results from a phase 1 trial for ALG.APV-527, a new bispecific antibody for cancer treatment. The drug met safety and effectiveness goals, with 56% of patients showing stable disease. Notably, it showed no serious liver toxicity, a common side effect in similar treatments. The trial involved patients with various solid tumors expressing the 5T4 antigen.

November 11, 2024
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