Finnish researchers find TIMP-1 protein enhances antitumor immunity, potentially improving cancer immunotherapies.
Researchers at the University of Turku in Finland discovered that TIMP-1, a protein known for preventing cell damage, plays a critical role in the immune system's defense against cancer. TIMP-1, produced by dendritic cells, enhances antitumor immunity by self-stimulation and activating surrounding immune cells. This finding could improve the effectiveness of current cancer immunotherapies, particularly for patients deficient in TIMP-1 expression.
June 14, 2024
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