University of Dundee scientists find leptin, an appetite-suppressing hormone, may prevent Alzheimer's development by reducing toxic protein effects.

Scientists at the University of Dundee discovered that a small part of an appetite-suppressing hormone called leptin, present in everyone, has dramatic effects on the brain, potentially stopping Alzheimer's disease development in its earliest stages. Leptin can reduce the effects of toxic proteins amyloid and tau, which cause memory loss and Alzheimer's progression. Researchers are working at the synapse level, where the disease process begins, aiming to slow or stop Alzheimer's development with leptin application.

May 20, 2024
7 Articles