NIH study finds 1.45-fold increased risk of blood clots in sickle cell trait carriers, consistent across diverse populations.

A study by NIH researchers has found that individuals with sickle cell trait, a carrier status for sickle cell disease, face a 1.45-fold increased risk of venous blood clots, including pulmonary embolism. This risk is consistent across diverse populations, not just those traditionally linked to sickle cell disease. Published in Blood Advances, these findings aim to enhance clinical practice guidelines and inform risks for surgeries and hospitalizations among affected individuals.

September 12, 2024
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