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Researchers used AI to study how protein mutations impact stability, advancing drug development for diseases like Alzheimer's.
Researchers at the Institute for Basic Science used AI, specifically AlphaFold2, to study how mutations impact protein stability, crucial for proper function and preventing diseases like Alzheimer's.
They found that AlphaFold's predicted structures carry significant physical information about stability.
This breakthrough could advance protein engineering and drug development in diseases caused by protein misfolding, and highlights AI's potential in biological research.
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Los investigadores usaron la IA para estudiar cómo las mutaciones proteicas impactan la estabilidad, avanzando en el desarrollo de fármacos para enfermedades como el Alzheimer.