Researchers find method to target glutamine metabolism in breast cancer cells, shrinking tumors.

Researchers at Cold Spring Harbor Laboratory discovered a method to deprive cancer cells of glutamine and its backup supply, effectively killing breast cancer cells and shrinking tumors. By targeting glutamine metabolism and its adaptive response, the team successfully treated cancer cells in lab dishes and mice, with potential improvements to glutamine metabolism inhibitors in the clinic. The approach could lead to new treatments targeting cancer's metabolic addictions.

August 28, 2024
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