Hokkaido University researchers developed a method to streamline antimicrobial drug candidate search, targeting MraY enzyme, potentially combating drug-resistant bacteria and AMR.
Researchers at Hokkaido University developed a new method to streamline the search for antimicrobial drug candidates, targeting an enzyme in bacterial cell membranes called phospho-N-acetylmuramoyl-pentapeptide-transferase (MraY). The innovative approach screens a wide variety of drug candidates without laborious purification steps, potentially advancing the fight against drug-resistant bacteria and the growing threat of antimicrobial resistance (AMR) in healthcare worldwide.
July 12, 2024
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