Researchers at the University of Michigan Medical School discover a pathway in normal wound healing that may reverse idiopathic pulmonary fibrosis (IPF) using a mouse model.
Researchers at the University of Michigan Medical School have discovered a pathway during normal wound healing that could potentially reverse idiopathic pulmonary fibrosis (IPF), a form of lung fibrosis with an unclear cause. Using a mouse model, the team simulated IPF by administering bleomycin, a chemotherapy agent that causes cell injury, and found that the resulting lung scarring resolved itself after about six weeks. This discovery may lead to new treatments for IPF, which currently has no cure and an average survival time of three to five years after diagnosis.
April 12, 2024
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