University of Basel researchers develop human lung microtissues using stem cells to study antibiotic-resistant Pseudomonas aeruginosa infection strategy in immunocompromised patients.
Researchers at the University of Basel's Biozentrum have developed human lung microtissues using stem cells to study how dangerous pathogen Pseudomonas aeruginosa, a WHO-listed antibiotic-resistant threat, invades the lungs. Their findings reveal the pathogen's infection strategy, which targets specific lung cells and breaks through the lungs' defenses, posing a significant threat to immunocompromised patients and those on mechanical ventilation. Mortality rates can reach 50%.
June 10, 2024
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