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Researchers find lipid PIP2 regulates SK2 channels, potentially leading to novel treatments for atrial fibrillation.
Researchers at Phoenix and UC Davis Health have identified a lipid, phosphatidylinositol 4,5-bisphosphate (PIP2), as a new target for treating atrial fibrillation (AFib), a common heart rhythm disorder affecting over 12 million people.
Their study highlights how PIP2 regulates small-conductance calcium-activated potassium channels (SK2), which are linked to heart failure.
These findings could lead to novel treatments for AFib and other cardiac arrhythmias.
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Los investigadores encuentran que el lípido PIP2 regula los canales SK2, lo que potencialmente conduce a tratamientos novedosos para la fibrilación auricular.