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Addex Therapeutics' experimental GABAB modulator reduces cough in primates with improved tolerability over baclofen.
Addex Therapeutics reports that its experimental GABAB positive allosteric modulator successfully reduced cough frequency in non-human primates with a favorable safety profile.
The drug showed anti-tussive effects comparable to baclofen, which is used off-label for cough but has side effects, while offering better tolerability.
The candidate is orally available and designed for once-daily dosing.
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El modulador experimental de GABAB de Addex Therapeutics reduce la tos en primates con una mejor tolerabilidad respecto al baclofeno.