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flag Addex Therapeutics' experimental GABAB modulator reduces cough in primates with improved tolerability over baclofen.

flag Addex Therapeutics reports that its experimental GABAB positive allosteric modulator successfully reduced cough frequency in non-human primates with a favorable safety profile. flag The drug showed anti-tussive effects comparable to baclofen, which is used off-label for cough but has side effects, while offering better tolerability. flag The candidate is orally available and designed for once-daily dosing.

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