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flag Experts warn standard naloxone doses may fail against potent fentanyl overdoses.

flag A new study warns that standard doses of naloxone may not fully reverse overdoses caused by potent synthetic opioids like fentanyl, which now account for a majority of U.S. opioid-related deaths. flag Because these drugs bind more tightly to receptors, the effects of naloxone can wear off quickly, leading to inadequate breathing even if a person appears awake. flag Experts urge immediate 911 activation and extended medical monitoring to address this critical gap in current overdose response guidelines.

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