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flag U.S. weight-loss drug prices dropped sharply in 2026 due to competition, with Zepbound and Wegovy now as low as $149–$299 monthly.

flag In 2026, intense competition has driven U.S. weight-loss drug prices down significantly, with Eli Lilly’s Zepbound and Wegovy now available for as little as $149 to $299 per month, down from over $1,000 and $1,600. flag This shift follows widespread insurance denials for obesity treatment, pushing patients like Ruth Gonzalez to pay out of pocket. flag Drugmakers are responding by selling directly to consumers via websites, retail partnerships with Walmart and Costco, and legal actions against off-label competitors. flag The trend has sparked debate over whether a direct-to-consumer model can increase transparency and reduce reliance on pharmacy benefit managers, with support from figures like former President Trump through his TrumpRx initiative. flag However, experts warn the price drops may not extend to other drugs due to lower demand and fewer competitors, leaving affordability a persistent challenge despite recent gains.

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