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flag Two Missouri residents, linked to international travel, have been confirmed with severe clade I mpox, the first cases in the state.

flag Two Missouri residents have been confirmed with clade I mpox, the first known cases in the state and the 13th and 14th nationally. flag Both individuals had recent international travel to regions where mpox is more common, and cases are unrelated with no local transmission. flag Clade I, which emerged globally in 2024, is more severe than the clade II strain from the 2022 outbreak and poses a higher risk of serious illness and death, especially for immunocompromised people. flag Health officials say the public risk remains low, but urge vaccination with the JYNNEOS vaccine for those at higher risk, including travelers to Central or Eastern Africa. flag Symptoms include fever, body aches, swollen lymph nodes, and a rash that progresses through stages. flag The virus spreads through close contact with lesions or contaminated materials. flag Individuals with symptoms should isolate until the rash heals.

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