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A new blood test detects early Alzheimer’s by identifying 3D shape changes in three proteins, enabling earlier and more accurate diagnosis.
A new blood test detects early Alzheimer’s by analyzing 3D structural changes in three key proteins—C1QA, clusterin, and apolipoprotein B—rather than their levels.
Using machine learning, researchers found these structural shifts, linked to disrupted protein folding, accurately distinguished between normal cognition, mild cognitive impairment, and Alzheimer’s.
The approach, more precise than traditional methods, may enable earlier diagnosis and better monitoring, offering promise for improved treatment and clinical trials.
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Un nuevo análisis de sangre detecta la enfermedad de Alzheimer temprana mediante la identificación de cambios de forma 3D en tres proteínas, lo que permite un diagnóstico más precoz y más preciso.