Duke upset by Siena in NCAA Tournament, ending 158-game streak of No. 1 seeds defeating No. 16 seeds.

In the 2026 NCAA Tournament, top-seeded Duke overcame a 13-point deficit to defeat 16-seed Siena 71-65, with Cameron Boozer scoring 22 points and grabbing 13 rebounds. Siena, playing all starters for the first time since 1979, nearly pulled off a historic upset, led by Gavin Doty’s 21 points, but Duke outscored them 39-22 in the second half. The win ended Duke’s 158-game streak of No. 1 seeds defeating No. 16 seeds, marking the first such upset since 2018. Duke will face TCU in the next round.