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Swedish study links Ozempic/Wegovy to lower depression, anxiety, and substance abuse risks.
A large Swedish study published in The Lancet Psychiatry in March 2026 links GLP-1 receptor agonist drugs like semaglutide, used in Ozempic and Wegovy, to significantly reduced risks of worsening depression, anxiety, and substance abuse.
Among over 95,000 patients with mental health conditions, semaglutide users saw a 44% lower risk of worsening depression and a 38% lower risk of worsening anxiety, along with a 47% drop in substance use disorder-related hospitalizations.
Liraglutide also showed benefits for depression.
The findings suggest potential mental health advantages for these diabetes and weight-loss medications, though researchers stress the need for further study to confirm causality and understand mechanisms.
Un estudio sueco vincula Ozempic/Wegovy con una disminución de la depresión, la ansiedad y el riesgo de abuso de sustancias.