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A compound in python blood, pTOS, reduces appetite and aids weight loss in mice without side effects, sparking potential for new human obesity treatments.
A compound in python blood called pTOS, produced by gut bacteria and naturally present in humans, spikes after eating and suppresses appetite in mice without causing side effects like nausea or muscle loss.
Found in Burmese pythons, pTOS helps them endure long fasts while maintaining metabolism and muscle mass.
In obese mice, it led to 9% weight loss over 28 days by acting on the brain’s hunger center.
Researchers believe it could lead to safer, more effective weight-loss treatments, with a startup, Arkana Therapeutics, developing synthetic versions.
Further studies are underway to test its effects in humans.
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Un compuesto en la sangre de la pitón, pTOS, reduce el apetito y ayuda a la pérdida de peso en ratones sin efectos secundarios, despertando el potencial para nuevos tratamientos de obesidad humana.