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Chinese scientists created a red blood cell-based capsule that delivers healthy mitochondria into cells, improving energy production and reversing symptoms in disease models.
Chinese researchers have developed a new mitochondrial capsule therapy using red blood cell membranes to deliver healthy mitochondria into cells, boosting delivery efficiency from under 5% to about 80%.
The method helps mitochondria evade cellular defenses, integrate into cells, and restore energy production.
In lab and animal studies, it reduced faulty mitochondria, improved cellular function, and reversed symptoms in models of Parkinson’s disease, Leigh syndrome, and mitochondrial DNA deletion syndrome, preventing neuron loss and extending lifespan.
The findings, published in Cell, suggest a potential new treatment for mitochondrial and neurodegenerative diseases.
Científicos chinos crearon una cápsula basada en glóbulos rojos que entrega mitocondrias sanas a las células, mejorando la producción de energía y revirtiendo los síntomas en modelos de enfermedades.