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Indian doctors used stem cells to treat infertility, leading to two successful births in women with severe uterine scarring.
Doctors at Sir Ganga Ram Hospital in New Delhi have reported two successful live births in India using umbilical cord-derived stem cell therapy to treat severe Asherman’s Syndrome, a condition causing infertility due to uterine scarring.
The experimental treatment, part of a clinical trial involving 10 women, involved injecting mesenchymal stem cells from Wharton’s jelly into the uterine lining under hysteroscopic guidance, aiming to regenerate damaged endometrial tissue without scaffolds.
Two patients, aged 39 and 40, showed improved endometrial thickness and menstrual flow, enabling successful frozen embryo transfers and deliveries of healthy babies at 35 and 31 weeks, respectively.
The results mark one of the first global reports of this scaffold-free approach and offer a potential fertility-restoring option for women with otherwise untreatable uterine damage, especially in India where surrogacy is restricted.
The trial continues with eight patients under follow-up.
Los médicos indios utilizaron células madre para tratar la infertilidad, lo que condujo a dos partos exitosos en mujeres con cicatrices uterinas severas.