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flag A 2025 White House claim linking acetaminophen to autism caused a sharp drop in its use during pregnancy and a surge in leucovorin prescriptions for autistic children, despite no new evidence.

flag In September 2025, a White House briefing linking acetaminophen use during pregnancy to autism and promoting leucovorin as a treatment resulted in a 10% decrease in acetaminophen prescriptions for pregnant women in emergency rooms, but no similar drop in non-pregnant patients. flag Outpatient leucovorin prescriptions for children aged 5 to 17 increased 71% above expectations, with autistic children accounting for 72% of the total. flag The changes occurred in the absence of new clinical evidence or guideline updates, demonstrating how high-profile political messaging can quickly shift medical practices despite a lack of scientific support. flag Tylenol use had returned to normal by December, but leucovorin prescriptions remained high. flag Medical experts warn that such unverified claims can jeopardize evidence-based care and public confidence in science.

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