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Chinese scientists created a non-invasive brain imaging system that tracks mouse brain changes over months with high resolution, aiding research on diseases like Alzheimer’s.
Chinese researchers have developed PACMes, a non-invasive brain imaging system that enables high-resolution, long-term visualization of the mouse brain through the intact scalp and skull without contrast agents.
The system, created by scientists at Southern University of Science and Technology in Shenzhen, uses near-infrared light and low-frequency sound combined with advanced computing to achieve 33-micrometer resolution across the entire cerebral cortex.
It supports continuous monitoring for over five months and captured the formation of new blood vessels within 72 hours after mild ischemic stroke in mice, offering insights into brain repair.
The technology advances research on chronic brain diseases like Alzheimer’s and epilepsy by enabling detailed, longitudinal study without surgery.
Findings were published in Science Advances.
Los científicos chinos crearon un sistema de imágenes cerebrales no invasivo que rastrea los cambios en el cerebro del ratón durante meses con alta resolución, ayudando a la investigación de enfermedades como el Alzheimer.