U.S. warns Americans in Iran and 14 Middle Eastern nations to leave due to escalating conflict and detentions following strikes that killed Iran’s Supreme Leader.

The U.S. State Department has issued a travel advisory urging Americans in Iran and 14 neighboring Middle Eastern countries to depart due to escalating conflict and heightened security risks following U.S.-Israeli strikes that killed Iran’s Supreme Leader. The warning, effective March 2, 2026, cites potential violence, instability, and disruptions, though it does not specify the threat’s source. Americans in Iran face increased danger, with at least six U.S. citizens or green-card holders reportedly detained, possibly in Evin Prison, and no official U.S. response outlined. The department advises travelers to consider evacuation, enroll in STEP, and monitor updates as conditions evolve.