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flag GLP-1 drugs like Ozempic may reduce heart damage after heart attacks by improving blood flow in tiny vessels, UK study finds.

flag GLP-1 weight-loss drugs like Ozempic and Wegovy may help reduce heart damage after a heart attack by preventing "no-reflow," a condition where tiny heart blood vessels stay blocked despite clearing the main artery, according to a UK study. flag In mouse models, the drugs relaxed pericytes—cells that constrict vessels during oxygen loss—by activating potassium channels, improving blood flow to damaged tissue. flag The findings, published in Nature Communications, suggest these drugs could be repurposed to improve recovery, possibly even administered by paramedics during emergencies. flag While prior research showed GLP-1 drugs lower cardiovascular risk independently of weight loss, this study offers a potential mechanism: enhanced microvascular blood flow. flag Human trials are needed to confirm benefits and determine best use.

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