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Phathom Pharmaceuticals exceeded revenue expectations in 2025, driven by strong sales of VOQUEZNA, and raised 2026 guidance while improving its financial position.
Phathom Pharmaceuticals reported Q4 2025 revenue of $57.6 million, beating estimates, and full-year 2025 revenue of $175.1 million, a 217% increase year-over-year, driven by over 1.1 million prescriptions for its drug VOQUEZNA.
The company raised 2026 revenue guidance to $320–345 million, expects operating profitability excluding stock-based compensation starting in Q3 2026, and cash-flow positivity in 2027.
It improved liquidity through a $130 million equity offering and debt restructuring, reducing its term loan to $175 million with lower interest and extended maturity to 2029.
A $17–20 million accounting shift will raise reported revenue but remain P&L neutral.
Despite near-term challenges, physician adoption and covered prescriptions are growing, signaling long-term potential in the gastrointestinal market.
Phathom Pharmaceuticals superó las expectativas de ingresos en 2025, impulsadas por las fuertes ventas de VOQUEZNA, y elevó la guía de 2026 al tiempo que mejoró su posición financiera.