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flag Phathom Pharmaceuticals exceeded revenue expectations in 2025, driven by strong sales of VOQUEZNA, and raised 2026 guidance while improving its financial position.

flag Phathom Pharmaceuticals reported Q4 2025 revenue of $57.6 million, beating estimates, and full-year 2025 revenue of $175.1 million, a 217% increase year-over-year, driven by over 1.1 million prescriptions for its drug VOQUEZNA. flag The company raised 2026 revenue guidance to $320–345 million, expects operating profitability excluding stock-based compensation starting in Q3 2026, and cash-flow positivity in 2027. flag It improved liquidity through a $130 million equity offering and debt restructuring, reducing its term loan to $175 million with lower interest and extended maturity to 2029. flag A $17–20 million accounting shift will raise reported revenue but remain P&L neutral. flag Despite near-term challenges, physician adoption and covered prescriptions are growing, signaling long-term potential in the gastrointestinal market.

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