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A promising nasal spray vaccine in mice offers broad, long-lasting protection against flu, COVID-19, colds, pneumonia, and allergens with just one dose, potentially eliminating annual shots, but human trials are still needed.
A nasal spray vaccine tested in mice shows promise in protecting against flu, COVID-19, common cold viruses, bacterial pneumonia, and allergens by training lung T cells to sustain innate immune responses.
One dose provided several months of broad protection, with researchers suggesting two doses may offer long-term immunity in humans, potentially eliminating the need for annual shots.
The approach, which mimics immune signals rather than targeting specific pathogens, could revolutionize respiratory disease prevention.
While experts call it a significant step forward, human trials are still needed, safety concerns remain, and a final product is likely years away.
Una prometedora vacuna con aerosol nasal en ratones ofrece una protección amplia y duradera contra la gripe, el COVID-19, los resfriados, la neumonía y los alérgenos con solo una dosis, lo que potencialmente elimina las inyecciones anuales, pero aún se necesitan ensayos en humanos.