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flag A 2026 study found AMD3100, an approved drug, helps immune cells attack rare liver cancer by reversing their exclusion from tumors.

flag A February 17, 2026, study in Gastroenterology reveals that AMD3100, an FDA-approved drug, may overcome immunotherapy resistance in fibrolamellar carcinoma, a rare liver cancer affecting young people. flag The research found tumor microenvironments trap immune T cells in fibrous regions, preventing cancer attack. flag AMD3100 reversed this T-cell exclusion, enabling T cells to reach tumors. flag Combined with immune checkpoint inhibitors, it significantly increased tumor cell death in patient samples. flag Because AMD3100 is already approved, clinical trials for this cancer could begin quickly.

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