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Aging men losing Y chromosomes face higher risks of heart disease, cancer, and shorter lives, new study finds.
Men naturally lose Y chromosomes with age, a condition affecting nearly half of older men, and new research links this mosaic loss of the Y chromosome (LOY) to higher risks of heart disease, certain cancers, cognitive decline, and shorter lifespans.
The loss, which occurs in blood and tissue cells, may impair cellular function and weaken immunity, though exact causes remain unclear.
While LOY is a growing marker of aging, scientists are studying whether it directly drives disease or is a symptom of broader aging processes, with potential future treatments still under development.
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Los hombres mayores que pierden los cromosomas Y se enfrentan a mayores riesgos de enfermedades del corazón, cáncer y vidas más cortas, según un nuevo estudio.