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flag Chinese brand CHANDO reveals 4-Butylresorcinol blocks pigmentation at genetic level, improving skin tone with minimal irritation.

flag At the 2026 IMCAS World Congress in Paris, Chinese skincare brand CHANDO unveiled a decade of research on its ingredient 4-Butylresorcinol (577), identifying a novel epigenetic mechanism that targets pigmentation at the genetic level. flag The study, led by scientist Dr. Youssef, found that 577 inhibits a microRNA involved in UV-induced melanin production, reducing key enzymes tied to dark spots and sallowness. flag Clinical testing showed the ingredient effectively improves skin tone with high tolerability and minimal irritation. flag The findings, presented during a keynote session, reflect CHANDO’s science-driven approach and its growing influence in global dermatological research. flag The ingredient is now part of CHANDO’s Cellcrystal Whitening Radiance Series.

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