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flag IIT Bombay researchers created a gentler method to harvest lab-grown T-cells using biodegradable scaffolds, improving survival and function for cancer immunotherapy.

flag Researchers at IIT Bombay have developed a gentler method to recover lab-grown T-cells for cancer immunotherapies using polycaprolactone scaffolds that mimic the body’s natural environment. flag Compared to traditional trypsin treatment, which damages cells, using the milder enzyme accutase significantly improved cell survival, preserved surface proteins, and maintained the cells’ ability to cluster and grow. flag The technique, published in Biomaterials Science, could enhance the effectiveness and scalability of CAR T-cell therapies, potentially making advanced treatments more accessible.

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