Christina Applegate reunited with "Married... With Children" cast at L.A. fundraiser for MS research, despite her multiple sclerosis diagnosis.

Christina Applegate reunited with her "Married With Children" co-stars Katey Sagal, Ed O’Neill, and David Faustino at a Los Angeles fundraiser on January 30, 2026, celebrating the sitcom’s 11-season run and 259 episodes. Despite managing multiple sclerosis, Applegate attended, calling her castmates “my family” and reflecting on their shared legacy. The event raised funds for the Race to Erase MS, a nonprofit dedicated to finding a cure for the disease.