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Scientists found 71 genes tied to mania in bipolar disorder, revealing it drives most genetic risk and differs from depression.
Researchers have identified 71 genetic variants linked specifically to mania in bipolar disorder, using data from over 600,000 individuals.
The study reveals mania drives over 80% of the disorder’s genetic variation and is distinct from depression, with stronger ties to wellbeing and education.
Many involved genes regulate calcium channels in brain cells, suggesting new treatment targets.
The findings could improve diagnosis accuracy and lead to personalized therapies.
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Los científicos encontraron 71 genes vinculados a la manía en el trastorno bipolar, revelando que impulsa la mayoría del riesgo genético y difiere de la depresión.