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High testosterone linked to lower heart disease risk in men with type 2 diabetes; higher estradiol linked to increased risk.
A Johns Hopkins Medicine study finds that higher testosterone levels at the start of a study were linked to lower heart disease risk in men with type 2 diabetes, while increases in estradiol over time were associated with higher risk, though no significant links were found in women.
The research, based on blood samples from the Look Ahead study and funded by the NIH, suggests sex hormones may help explain gender differences in cardiovascular outcomes among diabetic individuals, highlighting potential avenues for personalized prevention strategies.
Further research is needed to confirm findings.
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Altos niveles de testosterona asociados a un menor riesgo de enfermedad cardíaca en hombres con diabetes tipo 2; niveles más altos de estradiol asociados a un mayor riesgo.