The Broncos host the Bills on Sunday, January 16, 2026, in a 4:25 PM EST matchup on CBS.

The Denver Broncos host the Buffalo Bills in a Week 2 NFL matchup on Sunday, January 16, 2026. The game features a high-powered Bills offense led by quarterback Josh Allen, aiming to build on their strong start, while the Broncos seek to improve after a tough season opener. Key storylines include Denver’s defensive adjustments and Buffalo’s ability to sustain drives. The contest is set for 4:25 PM EST at Empower Field in Denver, broadcast on CBS.