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A bacterium in diabetic foot wounds blocks healing by damaging skin cells; breaking down its byproduct restores recovery.
Scientists in Singapore and Switzerland have found that a common bacterium in diabetic foot ulcers, Enterococcus faecalis, impairs wound healing by producing hydrogen peroxide through a metabolic process that damages skin cells.
This prevents cells from migrating to close wounds.
Adding the enzyme catalase, which breaks down hydrogen peroxide, reversed the damage and restored healing.
The approach, which avoids antibiotics and targets harmful byproducts instead of killing bacteria, could lead to new wound dressings to speed recovery, reduce infections, and prevent amputations.
The findings were published in Science Advances on January 17, 2026.
Una bacteria en las heridas del pie diabético bloquea la cicatrización dañando las células de la piel; la descomposición de su subproducto restaura la recuperación.