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flag U.S. overdose deaths dropped 21% to 73,000 in 12 months ending Aug 2025, the largest decline in decades.

flag U.S. overdose deaths declined to an estimated 73,000 in the 12 months ending August 2025, a 21% drop from the previous year, marking the longest sustained decrease in decades, following a 27% decline in 2024. flag Deaths fell in most states, though data from Arizona, Hawaii, Kansas, New Mexico, and North Dakota were incomplete or showed increases. flag Possible contributing factors include expanded access to naloxone, increased addiction treatment, changes in drug use patterns, opioid lawsuit settlements, and reduced fentanyl supply due to regulatory actions in China. flag Some researchers also suggest the end of pandemic stimulus payments may have played a role. flag Experts caution that the decline is likely due to multiple overlapping factors, and the trend has slowed, with overdose rates still far above pre-pandemic levels.

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