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A new Swiss method tracks how antibiotics kill individual bacteria in real time, showing it better predicts treatment success than old tests.
A new method developed by University of Basel researchers, antimicrobial single-cell testing (ASCT), uses high-resolution imaging to track how antibiotics kill individual bacteria over time, offering a more accurate measure of treatment effectiveness than traditional growth inhibition tests.
Tested on tuberculosis and related pathogens, the technique revealed that real-time killing, not just growth suppression, better predicts clinical outcomes and varies by bacterial strain and genetics.
The approach could lead to personalized antibiotic treatments and improved drug development, though it remains in research use for now.
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Un nuevo método suizo rastrea cómo los antibióticos matan bacterias individuales en tiempo real, demostrando que predice mejor el éxito del tratamiento que las pruebas antiguas.