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PFAS exposure triples fatty liver risk in teens, especially with certain genes or smoking, study finds.
A new study links exposure to PFAS "forever chemicals" to a nearly threefold increased risk of fatty liver disease (MASLD) in adolescents, especially those with a specific genetic variant or who smoke.
Analyzing 284 teens and young adults, researchers found higher blood levels of PFOA and PFHpA strongly associated with liver fat, using MRI scans and blood tests.
The findings, published in Environmental Research, highlight adolescence as a vulnerable period for long-term liver and metabolic health, with over 99% of Americans having detectable PFAS levels.
The study is the first to use gold-standard diagnostics to examine PFAS, genetics, and lifestyle interactions in youth, urging early action to reduce exposure through water filters and avoiding PFAS-containing products.
La exposición a PFAS triplica el riesgo de hígado graso en los adolescentes, especialmente con ciertos genes o el tabaquismo, según los hallazgos del estudio.