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flag Oprah Winfrey says GLP-1 medication helped her lose weight, quit drinking, and view obesity as a medical issue.

flag Oprah Winfrey, 71, revealed in a 2025 interview that her GLP-1 weight-loss medication, started in 2023, eliminated her desire to drink alcohol—a habit she once indulged in heavily, including consuming 17 shots of tequila in one night. flag She said the medication helped her lose weight, boost energy, and overcome long-standing shame around her weight, realizing obesity is a medical condition influenced by biology and environment, not personal failure. flag Winfrey, who regained weight after stopping the medication for a year, now views it as a lifelong necessity and advocates for compassion and informed health choices. flag She co-wrote a book on the topic set for release in January 2026.

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