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flag Israeli scientists developed a new immunotherapy targeting shared cancer mutations to treat drug-resistant prostate cancer.

flag Researchers at Israel's Weizmann Institute of Science have developed a new strategy to treat drug-resistant cancers by targeting shared mutations that cause resistance, using a tool called SpotNeoMet to identify common neo-antigens in metastatic prostate cancer. flag These neo-antigens, unique to cancer cells, triggered immune responses in lab and mouse models, offering a potential broad-spectrum immunotherapy approach. flag The findings, published in Cancer Discovery on December 29, 2025, could lead to scalable treatments for advanced cancers that no longer respond to standard therapies.

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