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Irish scientists enhanced lab-grown brain organoids with better blood vessels, improving their use in studying brain diseases.
Scientists at the University of Galway have improved lab-grown cerebral organoids by enabling deeper blood vessel growth, reducing cell death by up to threefold and supporting a blood-brain barrier-like structure.
Using a biocompatible hydrogel and vascular cells, researchers enhanced nutrient delivery in these mini-brain models, making them more physiologically relevant for studying Alzheimer’s, Parkinson’s, and stroke.
The findings, published in Advanced Science and involving collaborators from Ireland and the UK, mark a significant advancement in neuroscience research.
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Científicos irlandeses mejoraron organoides cerebrales cultivados en laboratorio con mejores vasos sanguíneos, mejorando su uso en el estudio de enfermedades cerebrales.