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AstraZeneca acquires global rights to Jacobio’s cancer drug JAB-23E73 in a $2B deal, with co-development in China.
Chinese biotech firm Jacobio Pharma has licensed its experimental pan-KRAS inhibitor JAB-23E73 to AstraZeneca in a deal worth up to $2 billion, including a $100 million upfront payment and potential milestone payments.
AstraZeneca gains exclusive rights outside mainland China, while both companies will co-develop and market the drug in China.
The Phase I drug targets KRAS mutations, common in pancreatic, colorectal, and lung cancers, affecting about 23% of all cancers.
Jacobio selected AstraZeneca for its global reach and oncology expertise to advance combination therapies.
Despite the deal’s significance, Jacobio’s shares dropped over 13% post-announcement, with some investors questioning the upfront cost, though the company defended the valuation as reasonable and emphasized long-term scientific goals.
AstraZeneca adquiere los derechos globales del medicamento contra el cáncer JAB-23E73 de Jacobio en un acuerdo de $ 2 mil millones, con desarrollo conjunto en China.