The 49ers need two wins to secure the NFC's No. 1 seed, while seven AFC playoff spots remain undecided.

The San Francisco 49ers are two wins away from securing the No. 1 seed in the NFC, needing victories over the Chicago Bears and Seattle Seahawks to guarantee a first-round bye. With an 8-2 record against NFC opponents, they control their fate, though the top seed could shift based on other results, including a Bears win or Packers loss for the NFC North title, or a Seahawks win over Carolina if the 49ers and Bears tie. In the AFC, the Broncos and Patriots are locked into playoff spots, while the Jaguars, Steelers, Chargers, and Texans remain in contention for division titles and playoff berths. Seven AFC playoff spots could be decided by the end of the weekend, with the Steelers potentially clinching the AFC North with a win over Cleveland.