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A major study finds no link between menopause HRT and dementia, supporting its use for symptoms, not prevention.
A major global review of over one million women finds no link between menopause hormone therapy (HRT) and dementia or mild cognitive impairment, regardless of timing, type, or duration.
The study, led by University College London and published in The Lancet Healthy Longevity, supports current guidance that HRT should be used for symptom relief—not dementia prevention—and aligns with recent U.S. FDA decisions to remove outdated dementia risk warnings.
Researchers note limitations in the data, including underrepresentation of certain groups, and call for more long-term studies.
Findings will inform upcoming World Health Organization dementia prevention guidelines in 2026.
Un estudio importante no encuentra ningún vínculo entre la HRT de la menopausia y la demencia, apoyando su uso para los síntomas, no para la prevención.