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A new nanoinjection system boosts doxorubicin’s cancer-killing power 23-fold and spares healthy tissue in lab tests.
A team from IIT Madras, Monash, and Deakin Universities has developed a nanoinjection system that delivers doxorubicin directly into breast cancer cells using thermally stable nanoarchaeosomes and silicon nanotubes, showing 23 times greater potency than free drug in lab tests.
The platform reduced tumor blood vessel formation, killed cancer cells, and spared healthy tissue, with potential to lower side effects and treatment costs.
It is being prepared for in vivo testing and regulatory review, with possible use in other cancers and broader access in low- and middle-income countries.
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Un nuevo sistema de nanoinyección aumenta el poder de la doxorubicina para matar el cáncer 23 veces y ahorra tejido sano en pruebas de laboratorio.