The 49ers will miss rookie WR Ricky Pearsall vs. Colts; LB Tatum Bethune returns from injury.

The San Francisco 49ers will be without rookie wide receiver Ricky Pearsall Jr. for their game against the Indianapolis Colts, as he remains sidelined due to injury. However, linebacker Tatum Bethune has been cleared to return to the lineup after missing time with his own injury. The team's updated injury report confirms these roster changes ahead of the matchup.