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flag Indian scientists find exocyst proteins critical for cellular cleanup, linking them to diseases like Alzheimer’s and cancer.

flag Indian scientists at JNCASR have found that seven of eight exocyst proteins are crucial for autophagy, a cellular cleanup process, in yeast models. flag The complex, previously linked to secretion, is essential for forming autophagosomes that remove damaged components. flag When disrupted, autophagy fails, leading to toxic buildup tied to Alzheimer’s, Parkinson’s, and cancer. flag The discovery reveals a new role for exocyst in cellular health and opens potential therapeutic avenues by targeting early autophagosome formation.

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