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flag Spain reports first non-travel-related mpox clade 1b case with human-to-human spread.

flag Spain has reported the first confirmed case of human-to-human transmission of the mpox clade 1b strain outside Africa, involving a 49-year-old Madrid man with no travel history to endemic regions. flag He had received two doses of the Imvanex vaccine, presented with genital ulcers and swollen lymph nodes, and reported sexual contact with two local partners who also had no travel links to Africa. flag PCR testing confirmed infection with clade 1b, marking the first instance of community spread without travel ties. flag The strain, first identified in the DRC in 2023, is highly transmissible. flag The WHO reported 2,501 new mpox cases and 12 deaths globally in October 2025. flag Health officials are urging preventive measures, especially for high-risk groups, and promoting non-stigmatizing communication.

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