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A study links the common BK virus to bladder cancer via immune system damage, even after the virus is gone.
A University of York study published in Science Advances suggests the BK virus, common in childhood and usually dormant, may trigger bladder cancer by causing DNA damage through the body’s immune response.
Researchers found that antiviral enzymes attack the virus but also harm nearby healthy cells—a "bystander effect"—creating mutations seen in cancer, even when the virus is no longer detectable.
This immune-driven damage may explain why BK virus is often absent in diagnosed cases.
The findings, based on lab analysis of human bladder cells, point to early viral control as a potential prevention strategy, especially for high-risk groups like transplant recipients.
Clinical trials are planned to confirm the link and explore ways to reduce bladder cancer risk by targeting the virus before it causes lasting harm.
Un estudio vincula el virus BK común al cáncer de vejiga a través del daño al sistema inmunológico, incluso después de que el virus haya desaparecido.